Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

In an in vitro screening for human carbonic anhydrase (hCA) inhibiting agents from higher plants, the petroleum ether and ethyl acetate extracts of Magydaris pastinacea seeds selectively inhibited hCA IX and hCA XII isoforms. The phytochemical investigation of the extracts led to the isolation of te...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Fois, Benedetta, Distinto, Simona, Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Floris, Costantino, Rosa, Antonella, Nieddu, Mariella, Caboni, Pierluigi, Sissi, Claudia, Angeli, Andrea, Supuran, Claudiu T., Cottiglia, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006766/
https://ncbi.nlm.nih.gov/pubmed/31948300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1713114
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