Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

In an in vitro screening for human carbonic anhydrase (hCA) inhibiting agents from higher plants, the petroleum ether and ethyl acetate extracts of Magydaris pastinacea seeds selectively inhibited hCA IX and hCA XII isoforms. The phytochemical investigation of the extracts led to the isolation of te...

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Bibliografski detalji
Izdano u:J Enzyme Inhib Med Chem
Glavni autori: Fois, Benedetta, Distinto, Simona, Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Floris, Costantino, Rosa, Antonella, Nieddu, Mariella, Caboni, Pierluigi, Sissi, Claudia, Angeli, Andrea, Supuran, Claudiu T., Cottiglia, Filippo
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006766/
https://ncbi.nlm.nih.gov/pubmed/31948300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1713114
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