Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

In an in vitro screening for human carbonic anhydrase (hCA) inhibiting agents from higher plants, the petroleum ether and ethyl acetate extracts of Magydaris pastinacea seeds selectively inhibited hCA IX and hCA XII isoforms. The phytochemical investigation of the extracts led to the isolation of te...

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書目詳細資料
發表在:J Enzyme Inhib Med Chem
Main Authors: Fois, Benedetta, Distinto, Simona, Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Floris, Costantino, Rosa, Antonella, Nieddu, Mariella, Caboni, Pierluigi, Sissi, Claudia, Angeli, Andrea, Supuran, Claudiu T., Cottiglia, Filippo
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2020
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006766/
https://ncbi.nlm.nih.gov/pubmed/31948300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1713114
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