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Development of aptamer-based inhibitors for CRISPR/Cas system

The occurrence of accidental mutations or deletions caused by genome editing with CRISPR/Cas9 system remains a critical unsolved problem of the technology. Blocking excess or prolonged Cas9 activity in cells is considered as one means of solving this problem. Here, we report the development of an in...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Zhao, Jing, Inomata, Rika, Kato, Yoshio, Miyagishi, Makoto
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897479/
https://ncbi.nlm.nih.gov/pubmed/33123724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa865
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