Repurposing the CRISPR-Cas9 system for targeted DNA methylation

Epigenetic studies relied so far on correlations between epigenetic marks and gene expression pattern. Technologies developed for epigenome editing now enable direct study of functional relevance of precise epigenetic modifications and gene regulation. The reversible nature of epigenetic modificatio...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Vojta, Aleksandar, Dobrinić, Paula, Tadić, Vanja, Bočkor, Luka, Korać, Petra, Julg, Boris, Klasić, Marija, Zoldoš, Vlatka
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Gene regulation, Chromatin and Epigenetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937303/
https://ncbi.nlm.nih.gov/pubmed/26969735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw159
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