Repurposing the CRISPR-Cas9 system for targeted DNA methylation

Epigenetic studies relied so far on correlations between epigenetic marks and gene expression pattern. Technologies developed for epigenome editing now enable direct study of functional relevance of precise epigenetic modifications and gene regulation. The reversible nature of epigenetic modificatio...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Vojta, Aleksandar, Dobrinić, Paula, Tadić, Vanja, Bočkor, Luka, Korać, Petra, Julg, Boris, Klasić, Marija, Zoldoš, Vlatka
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937303/
https://ncbi.nlm.nih.gov/pubmed/26969735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw159
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