Repurposing the CRISPR-Cas9 system for targeted DNA methylation

Epigenetic studies relied so far on correlations between epigenetic marks and gene expression pattern. Technologies developed for epigenome editing now enable direct study of functional relevance of precise epigenetic modifications and gene regulation. The reversible nature of epigenetic modificatio...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Vojta, Aleksandar, Dobrinić, Paula, Tadić, Vanja, Bočkor, Luka, Korać, Petra, Julg, Boris, Klasić, Marija, Zoldoš, Vlatka
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937303/
https://ncbi.nlm.nih.gov/pubmed/26969735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw159
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