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Development of aptamer-based inhibitors for CRISPR/Cas system

The occurrence of accidental mutations or deletions caused by genome editing with CRISPR/Cas9 system remains a critical unsolved problem of the technology. Blocking excess or prolonged Cas9 activity in cells is considered as one means of solving this problem. Here, we report the development of an in...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Zhao, Jing, Inomata, Rika, Kato, Yoshio, Miyagishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897479/
https://ncbi.nlm.nih.gov/pubmed/33123724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa865
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