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Development of aptamer-based inhibitors for CRISPR/Cas system

The occurrence of accidental mutations or deletions caused by genome editing with CRISPR/Cas9 system remains a critical unsolved problem of the technology. Blocking excess or prolonged Cas9 activity in cells is considered as one means of solving this problem. Here, we report the development of an in...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhao, Jing, Inomata, Rika, Kato, Yoshio, Miyagishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897479/
https://ncbi.nlm.nih.gov/pubmed/33123724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa865
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