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Zn(2+)-dependent DNAzymes that cleave all combinations of ribonucleotides

Although several DNAzymes are known, their utility is limited by a narrow range of substrate specificity. Here, we report the isolation of two zinc-dependent DNAzymes, ZincDz1 and ZincDz2, which exhibit compact catalytic core sequences with highly versatile hydrolysis activity. They were selected th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Commun Biol
मुख्य लेखकों: Inomata, Rika, Zhao, Jing, Miyagishi, Makoto
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886857/
https://ncbi.nlm.nih.gov/pubmed/33594202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01738-6
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