DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins

Changes in N-glycosylation of plasma proteins are observed in many types of cancer, nevertheless, few studies suggest the exact mechanism involved in aberrant protein glycosylation. Here we studied the impact of DNA methylation on the N-glycome in the secretome of the HepG2 cell line derived from he...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Klasić, Marija, Krištić, Jasminka, Korać, Petra, Horvat, Tomislav, Markulin, Dora, Vojta, Aleksandar, Reiding, Karli R., Wuhrer, Manfred, Lauc, Gordan, Zoldoš, Vlatka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829869/
https://ncbi.nlm.nih.gov/pubmed/27073020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24363
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