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DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins

Changes in N-glycosylation of plasma proteins are observed in many types of cancer, nevertheless, few studies suggest the exact mechanism involved in aberrant protein glycosylation. Here we studied the impact of DNA methylation on the N-glycome in the secretome of the HepG2 cell line derived from he...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Klasić, Marija, Krištić, Jasminka, Korać, Petra, Horvat, Tomislav, Markulin, Dora, Vojta, Aleksandar, Reiding, Karli R., Wuhrer, Manfred, Lauc, Gordan, Zoldoš, Vlatka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829869/
https://ncbi.nlm.nih.gov/pubmed/27073020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24363
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