Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth

Hedgehog (Hh) signaling plays a critical role in embryogenesis and tissue homeostasis, and its deregulation has been associated with tumor growth. The tumor suppressor SuFu inhibits Hh signaling by preventing the nuclear translocation of Gli and suppressing cell proliferation. Regulation of SuFu act...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Yan, Zhengwei, Cheng, Minzhang, Hu, Guohui, Wang, Yao, Zeng, Shaopeng, Huang, Aidi, Xu, Linlin, Liu, Yuan, Shi, Chao, Deng, Libin, Lu, Quqin, Rao, Hai, Lu, Hua, Chen, Ye-Guang, Luo, Shiwen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896051/
https://ncbi.nlm.nih.gov/pubmed/33608498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03487-0
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker