Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway

Suppressor of Fused (SuFu), one of the most conserved components of the Hedgehog (Hh) signaling, binds Gli transcription factors and impedes activation of target gene expression in mammalian cells. Despite the central importance of SuFu in the Hh pathway, little is known about SuFu regulation. In a...

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Udgivet i:Int J Oncol
Main Authors: Zhou, Fen, Huang, Dengliang, Li, Yong, Hu, Guanghui, Rao, Hai, Lu, Quqin, Luo, Shiwen, Wang, Yao
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238777/
https://ncbi.nlm.nih.gov/pubmed/28035348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3819
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