Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway

Suppressor of Fused (SuFu), one of the most conserved components of the Hedgehog (Hh) signaling, binds Gli transcription factors and impedes activation of target gene expression in mammalian cells. Despite the central importance of SuFu in the Hh pathway, little is known about SuFu regulation. In a...

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Bibliografiska uppgifter
I publikationen:Int J Oncol
Huvudupphovsmän: Zhou, Fen, Huang, Dengliang, Li, Yong, Hu, Guanghui, Rao, Hai, Lu, Quqin, Luo, Shiwen, Wang, Yao
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2016
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238777/
https://ncbi.nlm.nih.gov/pubmed/28035348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3819
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