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Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes

BACKGROUND: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. METHODS: R...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Yang, Yanli, Li, Jun, Geng, Yinghua, Liu, Lin, Li, Dianming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://ncbi.nlm.nih.gov/pubmed/33080073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23597
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