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Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes

BACKGROUND: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. METHODS: R...

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Pubblicato in:J Clin Lab Anal
Autori principali: Yang, Yanli, Li, Jun, Geng, Yinghua, Liu, Lin, Li, Dianming
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://ncbi.nlm.nih.gov/pubmed/33080073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23597
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