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Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes

BACKGROUND: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. METHODS: R...

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Podrobná bibliografie
Vydáno v:J Clin Lab Anal
Hlavní autoři: Yang, Yanli, Li, Jun, Geng, Yinghua, Liu, Lin, Li, Dianming
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://ncbi.nlm.nih.gov/pubmed/33080073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23597
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