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Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes

BACKGROUND: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. METHODS: R...

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Bibliografiske detaljer
Udgivet i:J Clin Lab Anal
Main Authors: Yang, Yanli, Li, Jun, Geng, Yinghua, Liu, Lin, Li, Dianming
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://ncbi.nlm.nih.gov/pubmed/33080073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23597
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