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Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes

BACKGROUND: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. METHODS: R...

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Библиографические подробности
Опубликовано в: :J Clin Lab Anal
Главные авторы: Yang, Yanli, Li, Jun, Geng, Yinghua, Liu, Lin, Li, Dianming
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://ncbi.nlm.nih.gov/pubmed/33080073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23597
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