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Thyroid Hormone Receptor α Mutations Cause Heart Defects in Zebrafish

Background: Mutations of thyroid hormone receptor α1 (TRα1) cause resistance to thyroid hormone (RTHα). Patients exhibit growth retardation, delayed bone development, anemia, and bradycardia. By using mouse models of RTHα, much has been learned about the molecular actions of TRα1 mutants that underl...

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Vydáno v:Thyroid
Hlavní autoři: Han, Cho Rong, Wang, Hui, Hoffmann, Victoria, Zerfas, Patricia, Kruhlak, Michael, Cheng, Sheue-Yann
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891307/
https://ncbi.nlm.nih.gov/pubmed/32762296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0332
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