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Thyroid Hormone Receptor α Mutations Cause Heart Defects in Zebrafish

Background: Mutations of thyroid hormone receptor α1 (TRα1) cause resistance to thyroid hormone (RTHα). Patients exhibit growth retardation, delayed bone development, anemia, and bradycardia. By using mouse models of RTHα, much has been learned about the molecular actions of TRα1 mutants that underl...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Han, Cho Rong, Wang, Hui, Hoffmann, Victoria, Zerfas, Patricia, Kruhlak, Michael, Cheng, Sheue-Yann
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891307/
https://ncbi.nlm.nih.gov/pubmed/32762296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0332
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