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Thyroid Hormone Receptor α Mutations Cause Heart Defects in Zebrafish

Background: Mutations of thyroid hormone receptor α1 (TRα1) cause resistance to thyroid hormone (RTHα). Patients exhibit growth retardation, delayed bone development, anemia, and bradycardia. By using mouse models of RTHα, much has been learned about the molecular actions of TRα1 mutants that underl...

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Bibliografische gegevens
Gepubliceerd in:Thyroid
Hoofdauteurs: Han, Cho Rong, Wang, Hui, Hoffmann, Victoria, Zerfas, Patricia, Kruhlak, Michael, Cheng, Sheue-Yann
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc., publishers 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891307/
https://ncbi.nlm.nih.gov/pubmed/32762296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0332
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