Alzheimer’s disease brain contains tau fractions with differential prion-like activities

Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer’s disease (AD) and related tauopathies. Regional distribution of NFTs is associated with the progression of the disease and has been proposed to be a result of prion-like propagation of misfolded ta...

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Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Li, Longfei, Shi, Ruirui, Gu, Jianlan, Tung, Yunn Chyn, Zhou, Yan, Zhou, Dingwei, Wu, Ruozhen, Chu, Dandan, Jin, Nana, Deng, Kevin, Xu, Jiawei, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890974/
https://ncbi.nlm.nih.gov/pubmed/33597014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01127-4
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