SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts With KRAS Q61R Mutant Protein in Colorectal Carcinoma

CONTEXT. NRAS is a member of the RAS family oncoproteins implicated in cancer. Gain-of-function NRAS mutations were reported in a subset of colorectal cancers. These mutations occur at codons 12, 13, and 61 and are detected by molecular genetic testing. Recently, an antibody (clone SP174) became ava...

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Udgivet i:Arch Pathol Lab Med
Main Authors: Lasota, Jerzy, Kowalik, Artur, Felisiak-Golabek, Anna, Inaguma, Shingo, Wang, Zeng-Feng, Pięciak, Liliana, Zięba, Sebastian, Pęksa, Rafał, Kopczynski, Janusz, Okoń, Krzysztof, Waloszczyk, Piotr, Gozdz, Stanislaw, Biernat, Wojciech, Miettinen, Markku
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888553/
https://ncbi.nlm.nih.gov/pubmed/28353383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5858/arpa.2016-0147-OA
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