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Variation of mutant allele frequency in NRAS Q61 mutated melanomas
BACKGROUND: Somatic mutations of BRAF or NRAS activating the MAP kinase cell signaling pathway are present in 70% of cutaneous melanomas. The mutant allele frequency of BRAF V600E (M%BRAF) was recently shown to be highly heterogeneous in melanomas. The present study focuses on the NRAS Q61 mutant al...
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| Publicado no: | BMC Dermatol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494128/ https://ncbi.nlm.nih.gov/pubmed/28668077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12895-017-0061-x |
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