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Variation of mutant allele frequency in NRAS Q61 mutated melanomas
BACKGROUND: Somatic mutations of BRAF or NRAS activating the MAP kinase cell signaling pathway are present in 70% of cutaneous melanomas. The mutant allele frequency of BRAF V600E (M%BRAF) was recently shown to be highly heterogeneous in melanomas. The present study focuses on the NRAS Q61 mutant al...
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| 出版年: | BMC Dermatol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494128/ https://ncbi.nlm.nih.gov/pubmed/28668077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12895-017-0061-x |
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