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Variations of BRAF mutant allele percentage in melanomas
BACKGROUND: BRAF mutations are present in 40 % of human skin melanomas. Mutated tumors with an increased percentage of BRAF mutant alleles (BRAF-M%) may have a better response to RAF/MEK inhibitors. We evaluated the BRAF-M% in melanomas, and the genetic causes of its variation. METHODS: BRAF-M% was...
Shranjeno v:
| izdano v: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491198/ https://ncbi.nlm.nih.gov/pubmed/26141748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1515-3 |
| Oznake: |
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