Laddar...
New Mechanisms of mTOR Pathway Activation in KIT-mutant Malignant GISTs
A great majority of gastrointestinal stromal tumors (GISTs) are primarily driven by gain-of-function KIT receptor tyrosine kinase mutations that subsequently lead to activation of phosphatidiylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathway, a downstream effector of KIT signali...
Sparad:
| I publikationen: | Appl Immunohistochem Mol Morphol |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2019
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8191381/ https://ncbi.nlm.nih.gov/pubmed/28777148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0000000000000541 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|