Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

In acute myeloid leukemia (AML), molecular heterogeneity across patients constitutes a major challenge for prognosis and therapy. AML with NPM1 mutation is a distinct genetic entity in the revised World Health Organization classification. However, differing patterns of co-mutation and response to th...

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Sparad:
Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Mer, Arvind Singh, Heath, Emily M., Madani Tonekaboni, Seyed Ali, Dogan-Artun, Nergiz, Nair, Sisira Kadambat, Murison, Alex, Garcia-Prat, Laura, Shlush, Liran, Hurren, Rose, Voisin, Veronique, Bader, Gary D., Nislow, Corey, Rantalainen, Mattias, Lehmann, Soren, Gower, Mark, Guidos, Cynthia J., Lupien, Mathieu, Dick, John E., Minden, Mark D., Schimmer, Aaron D., Haibe-Kains, Benjamin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886883/
https://ncbi.nlm.nih.gov/pubmed/33594052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21233-0
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