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Pathway-Based Drug Response Prediction Using Similarity Identification in Gene Expression

Lapatinib and trastuzumab (Herceptin) are targeted therapies designed for patients with HER2+ breast tumors. Although these therapies improved survival rates of patients with this tumor type, not all the patients harboring HER2 amplification respond to these drugs. The NeoALTTO clinical trial was de...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Madani Tonekaboni, Seyed Ali, Beri, Gangesh, Haibe-Kains, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509171/
https://ncbi.nlm.nih.gov/pubmed/33033492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.01016
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