Microbiota metabolism promotes synthesis of the human Ah receptor agonist 2,8-dihydroxyquinoline

The Aryl hydrocarbon receptor (AHR) is a major regulator of immune function within the gastrointestinal tract. Resident microbiota are capable of influencing AHR-dependent signaling pathways via production of an array of bioactive molecules that act as AHR agonists, such as indole or indole-3-aldehy...

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Bibliografiske detaljer
Udgivet i:J Proteome Res
Main Authors: Hubbard, Troy D., Liu, Qing, Murray, Iain A., Dong, Fangcong, Miller, Charles, Smith, Phillip B., Gowda, Krishne, Lin, Jyh Ming, Amin, Shantu, Patterson, Andrew D., Perdew, Gary H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886227/
https://ncbi.nlm.nih.gov/pubmed/30777439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00946
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