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Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor recognized for its role in xenobiotic metabolism. The physiologic function of AHR has expanded to include roles in immune regulation, organogenesis, mucosal barrier function, and the cell cycle. These functions are likely...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Hubbard, Troy D., Murray, Iain A., Perdew, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576673/
https://ncbi.nlm.nih.gov/pubmed/26041783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.064246
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