Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

Ligand activation of the aryl hydrocarbon (AHR) has profound effects upon the immunological status of the gastrointestinal tract, establishing and maintaining signaling networks, which facilitate host-microbe homeostasis at the mucosal interface. However, the identity of the ligand(s) responsible fo...

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Vydáno v:Sci Rep
Hlavní autoři: Hubbard, Troy D., Murray, Iain A., Bisson, William H., Lahoti, Tejas S., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522678/
https://ncbi.nlm.nih.gov/pubmed/26235394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12689
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