Selective Ah Receptor Ligands Mediate Enhanced SREBP1 Proteolysis to Restrict Lipogenesis in Sebocytes

The aryl hydrocarbon receptor (AHR) mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced toxicity that can lead to chloracne in humans. A characteristic of chloracne, in contrast to acne vulgaris, is shrinkage or loss of sebaceous glands. Acne vulgaris, on the other hand, is often accompanied...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxicol Sci
Egile Nagusiak: Muku, Gulsum E, Blazanin, Nicholas, Dong, Fangcong, Smith, Philip B, Thiboutot, Diane, Gowda, Krishne, Amin, Shantu, Murray, Iain A, Perdew, Gary H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Molecular, Biochemical and Systems Toxicology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736396/
https://ncbi.nlm.nih.gov/pubmed/31225620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz140
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