Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses

The Ah receptor (AHR) has been shown to exhibit both inflammatory and anti-inflammatory activity in a context-specific manner. In vivo macrophage-driven acute inflammation models were utilized here to test whether the selective Ah receptor modulator 1-allyl-7-trifluoromethyl-1H–indazol-3-yl]-4-metho...

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Pubblicato in:Lab Invest
Autori principali: Muku, Gulsum E., Lahoti, Tejas S., Murray, Iain A., Podolsky, Michael A., Smith, Kayla J., Hubbard, Troy D., Kuzu, Guray, Gowda, Krishne, Amin, Shantu G., Perdew, Gary H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711556/
https://ncbi.nlm.nih.gov/pubmed/28892097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.92
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