Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets

Connexins oligomerise to form hexameric hemichannels in the plasma membrane that can further dock together on adjacent cells to form gap junctions and facilitate intercellular trafficking of molecules. In this study, we report the expression and function of an orphan connexin, connexin-62 (Cx62), in...

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Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Sahli, Khaled A., Flora, Gagan D., Sasikumar, Parvathy, Maghrabi, Ali H., Holbrook, Lisa-Marie, AlOuda, Sarah K., Elgheznawy, Amro, Sage, Tanya, Stainer, Alexander R., Adiyaman, Recep, AboHassan, Mohammad, Crescente, Marilena, Kriek, Neline, Vaiyapuri, Sakthivel, Bye, Alexander P., Unsworth, Amanda J., Jones, Chris I., McGuffin, Liam J., Gibbins, Jonathan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2021
Ämnen:
Thrombosis and Hemostasis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885822/
https://ncbi.nlm.nih.gov/pubmed/32822477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004575
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