Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets

Connexins oligomerise to form hexameric hemichannels in the plasma membrane that can further dock together on adjacent cells to form gap junctions and facilitate intercellular trafficking of molecules. In this study, we report the expression and function of an orphan connexin, connexin-62 (Cx62), in...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Blood
Main Authors: Sahli, Khaled A., Flora, Gagan D., Sasikumar, Parvathy, Maghrabi, Ali H., Holbrook, Lisa-Marie, AlOuda, Sarah K., Elgheznawy, Amro, Sage, Tanya, Stainer, Alexander R., Adiyaman, Recep, AboHassan, Mohammad, Crescente, Marilena, Kriek, Neline, Vaiyapuri, Sakthivel, Bye, Alexander P., Unsworth, Amanda J., Jones, Chris I., McGuffin, Liam J., Gibbins, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2021
Assuntos:
Thrombosis and Hemostasis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885822/
https://ncbi.nlm.nih.gov/pubmed/32822477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004575
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares