FXR and its ligands inhibit the function of platelets

OBJECTIVE: While initially seemingly paradoxical due to the lack of nucleus, platelets possess a number of transcription factors that regulate their function through DNA-independent mechanisms. These include the Farnesoid X Receptor (FXR), a member of the superfamily of ligand-activated transcriptio...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Moraes, Leonardo A., Unsworth, Amanda J., Vaiyapuri, Sakthivel, Ali, Marfoua S., Sasikumar, Parvathy, Sage, Tanya, Flora, Gagan D, Bye, Alex P, Kriek, Neline, Dorchies, Emilie, Molendi-Coste, Olivier, Dombrowicz, David, Staels, Bart, Bishop-Bailey, David, Gibbins, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144997/
https://ncbi.nlm.nih.gov/pubmed/27758768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308093
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