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RXR Ligands Negatively Regulate Thrombosis and Hemostasis

OBJECTIVE—: Platelets have been found to express intracellular nuclear receptors including the retinoid X receptors (RXRα and RXRβ). Treatment of platelets with ligands of RXR has been shown to inhibit platelet responses to ADP and thromboxane A2; however, the effects on responses to other platelet...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Unsworth, Amanda J., Flora, Gagan D., Sasikumar, Parvathy, Bye, Alexander P., Sage, Tanya, Kriek, Neline, Crescente, Marilena, Gibbins, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405776/
https://ncbi.nlm.nih.gov/pubmed/28254816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309207
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