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Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing
Cytosine base editors and adenine base editors (ABEs) can correct point mutations predictably and independent of Cas9-induced double-stranded DNA breaks (which causes substantial indel formation) and homology-directed repair (which typically leads to low editing efficiency). Here, we show, in adult...
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| Publicado no: | Nat Biomed Eng |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885272/ https://ncbi.nlm.nih.gov/pubmed/33077938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-00632-6 |
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