An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

The retinal pigment epithelium (RPE) provides vital metabolic support for retinal photoreceptor cells and is an important player in numerous retinal diseases. Gene manipulation in mice using the Cre-LoxP system is an invaluable tool for studying the genetic basis of these retinal diseases. However,...

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Vydáno v:JCI Insight
Hlavní autoři: Choi, Elliot H., Suh, Susie, Einstein, David E., Leinonen, Henri, Dong, Zhiqian, Rao, Sriganesh Ramachandra, Fliesler, Steven J., Blackshaw, Seth, Yu, Minzhong, Peachey, Neal S., Palczewski, Krzysztof, Kiser, Philip D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2021
Témata:
Technical Advance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262343/
https://ncbi.nlm.nih.gov/pubmed/33784255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.146604
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