An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

The retinal pigment epithelium (RPE) provides vital metabolic support for retinal photoreceptor cells and is an important player in numerous retinal diseases. Gene manipulation in mice using the Cre-LoxP system is an invaluable tool for studying the genetic basis of these retinal diseases. However,...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Choi, Elliot H., Suh, Susie, Einstein, David E., Leinonen, Henri, Dong, Zhiqian, Rao, Sriganesh Ramachandra, Fliesler, Steven J., Blackshaw, Seth, Yu, Minzhong, Peachey, Neal S., Palczewski, Krzysztof, Kiser, Philip D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2021
Assuntos:
Technical Advance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262343/
https://ncbi.nlm.nih.gov/pubmed/33784255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.146604
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