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Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing
Cytosine base editors and adenine base editors (ABEs) can correct point mutations predictably and independent of Cas9-induced double-stranded DNA breaks (which causes substantial indel formation) and homology-directed repair (which typically leads to low editing efficiency). Here, we show, in adult...
में बचाया:
| में प्रकाशित: | Nat Biomed Eng |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885272/ https://ncbi.nlm.nih.gov/pubmed/33077938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-00632-6 |
| टैग : |
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