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Dendritic cell-derived TGF-β mediates the induction of mucosal regulatory T cell response to Helicobacter infection essential for maintenance of immune tolerance in mice

BACKGROUND: Helicobacter pylori infection leads to regulatory T-cell (Treg) induction in infected mice, which contributes to H. pylori immune escape. However, the mechanisms responsible for H. pylori induction of Treg and immune tolerance remain unclear. We hypothesized DC-produced TGF-β may be resp...

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Bibliografski detalji
Izdano u:Helicobacter
Glavni autori: Owyang, Stephanie Y., Zhang, Min, El-Zaatari, Mohamad, Eaton, Kathryn A., Bishu, Shrinivas, Hou, Guoqing, Grasberger, Helmut, Kao, John Y.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885176/
https://ncbi.nlm.nih.gov/pubmed/33025641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hel.12763
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