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Dual Oxidases Control Release of Hydrogen Peroxide by the Gastric Epithelium to Prevent Helicobacter felis Infection and Inflammation in Mice

BACKGROUND & AIMS: Dual oxidases (DUOX) are conserved NADPH oxidases that produce H(2)O(2) at the epithelial cell surface. The DUOX enzyme comprises the DUOX and DUOXA (DUOX maturation factor) subunits. Mammalian genomes encode 2 DUOX isoenzymes (DUOX1–DUOXA1 and DUOX2–DUOXA2). Expression of the...

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Detalhes bibliográficos
Main Authors: Grasberger, Helmut, El-Zaatari, Mohamad, Merchant, Juanita L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805753/
https://ncbi.nlm.nih.gov/pubmed/23860501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.011
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