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Dual Oxidases Control Release of Hydrogen Peroxide by the Gastric Epithelium to Prevent Helicobacter felis Infection and Inflammation in Mice
BACKGROUND & AIMS: Dual oxidases (DUOX) are conserved NADPH oxidases that produce H(2)O(2) at the epithelial cell surface. The DUOX enzyme comprises the DUOX and DUOXA (DUOX maturation factor) subunits. Mammalian genomes encode 2 DUOX isoenzymes (DUOX1–DUOXA1 and DUOX2–DUOXA2). Expression of the...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805753/ https://ncbi.nlm.nih.gov/pubmed/23860501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.011 |
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