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Increased Expression of DUOX2 is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

BACKGROUND & AIMS: Dual oxidase 2 (DUOX2), a hydrogen-peroxide generator at the apical membrane of gastrointestinal epithelia, is upregulated in patients with inflammatory bowel disease (IBD) before the onset of inflammation, but little is known about its effects. We investigated the role of DUO...

詳細記述

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書誌詳細
出版年:Gastroenterology
主要な著者: Grasberger, Helmut, Gao, Jun, Nagao-Kitamoto, Hiroko, Kitamoto, Sho, Zhang, Min, Kamada, Nobuhiko, Eaton, Kathryn A., El-Zaatari, Mohamad, Shreiner, Andrew B., Merchant, Juanita L., Owyang, Chung, Kao, John Y.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663159/
https://ncbi.nlm.nih.gov/pubmed/26261005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.07.062
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