Increased Expression of DUOX2 is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

BACKGROUND & AIMS: Dual oxidase 2 (DUOX2), a hydrogen-peroxide generator at the apical membrane of gastrointestinal epithelia, is upregulated in patients with inflammatory bowel disease (IBD) before the onset of inflammation, but little is known about its effects. We investigated the role of DUO...

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Bibliografiset tiedot
Julkaisussa:Gastroenterology
Päätekijät: Grasberger, Helmut, Gao, Jun, Nagao-Kitamoto, Hiroko, Kitamoto, Sho, Zhang, Min, Kamada, Nobuhiko, Eaton, Kathryn A., El-Zaatari, Mohamad, Shreiner, Andrew B., Merchant, Juanita L., Owyang, Chung, Kao, John Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663159/
https://ncbi.nlm.nih.gov/pubmed/26261005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.07.062
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