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CCR2 mediates Helicobacter pylori-induced immune tolerance and contributes to mucosal homeostasis

BACKGROUND: We previously demonstrated that H. pylori infection leads to increased induction of regulatory T cells (Treg) in local and systemic immune compartments. Here we investigate the role of CCR2 in the tolerogenic programing of dendritic cells (DC) in a mouse model of H. pylori infection. MAT...

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Detalhes bibliográficos
Publicado no:Helicobacter
Main Authors: Sun, Xia, Zhang, Min, El-Zataari, Mohamad, Huffnagle, Gray B., Kao, John Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352485/
https://ncbi.nlm.nih.gov/pubmed/27933701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hel.12366
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