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Zoledronate promotes inflammatory cytokine expression in human CD14‐positive monocytes among peripheral mononuclear cells in the presence of γδ T cells

Bisphosphonates distributed to bone exert toxic effects specifically towards osteoclasts. On the other hand, intravenous administration of a nitrogen‐containing bisphosphonate (N‐BP) such as zoledronate induces acute‐phase reactions (APRs), including influenza‐like fever 1 day later, indicating an i...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Takimoto, Reiko, Suzawa, Tetsuo, Yamada, Atsushi, Sasa, Kiyohito, Miyamoto, Yoichi, Yoshimura, Kentaro, Sasama, Yuji, Tanaka, Motohiro, Kinoshita, Mitsuhiro, Ikezaki, Kaori, Ichikawa, Makoto, Yamamoto, Matsuo, Shirota, Tatsuo, Kamijo, Ryutaro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884644/
https://ncbi.nlm.nih.gov/pubmed/33131052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13283
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