Monocarboxylate Transporter-1 Is Required for Cell Death in Mouse Chondrocytic ATDC5 Cells Exposed to Interleukin-1β via Late Phase Activation of Nuclear Factor κB and Expression of Phagocyte-type NADPH Oxidase

Interleukin-1β (IL-1β) induces cell death in chondrocytes in a nitric oxide (NO)- and reactive oxygen species (ROS)-dependent manner. In this study, increased production of lactate was observed in IL-1β-treated mouse chondrocytic ATDC5 cells prior to the onset of their death. IL-1β-induced cell deat...

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Autores principales: Yoshimura, Kentaro, Miyamoto, Yoichi, Yasuhara, Rika, Maruyama, Toshifumi, Akiyama, Tomohito, Yamada, Atsushi, Takami, Masamichi, Suzawa, Tetsuo, Tsunawaki, Shoko, Tachikawa, Tetsuhiko, Baba, Kazuyoshi, Kamijo, Ryutaro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083201/
https://ncbi.nlm.nih.gov/pubmed/21372137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221259
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