Porphyromonas gingivalis-derived Lysine Gingipain Enhances Osteoclast Differentiation Induced by Tumor Necrosis Factor-α and Interleukin-1β but Suppresses That by Interleukin-17A: IMPORTANCE OF PROTEOLYTIC DEGRADATION OF OSTEOPROTEGERIN BY LYSINE GINGIPAIN

Periodontitis is a chronic inflammatory disease accompanied by alveolar bone resorption by osteoclasts. Porphyromonas gingivalis, an etiological agent for periodontitis, produces cysteine proteases called gingipains, which are classified based on their cleavage site specificity (i.e. arginine (Rgps)...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Akiyama, Tomohito, Miyamoto, Yoichi, Yoshimura, Kentaro, Yamada, Atsushi, Takami, Masamichi, Suzawa, Tetsuo, Hoshino, Marie, Imamura, Takahisa, Akiyama, Chie, Yasuhara, Rika, Mishima, Kenji, Maruyama, Toshifumi, Kohda, Chikara, Tanaka, Kazuo, Potempa, Jan, Yasuda, Hisataka, Baba, Kazuyoshi, Kamijo, Ryutaro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140917/
https://ncbi.nlm.nih.gov/pubmed/24755218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520510
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky