Porphyromonas gingivalis-derived Lysine Gingipain Enhances Osteoclast Differentiation Induced by Tumor Necrosis Factor-α and Interleukin-1β but Suppresses That by Interleukin-17A: IMPORTANCE OF PROTEOLYTIC DEGRADATION OF OSTEOPROTEGERIN BY LYSINE GINGIPAIN

Periodontitis is a chronic inflammatory disease accompanied by alveolar bone resorption by osteoclasts. Porphyromonas gingivalis, an etiological agent for periodontitis, produces cysteine proteases called gingipains, which are classified based on their cleavage site specificity (i.e. arginine (Rgps)...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Akiyama, Tomohito, Miyamoto, Yoichi, Yoshimura, Kentaro, Yamada, Atsushi, Takami, Masamichi, Suzawa, Tetsuo, Hoshino, Marie, Imamura, Takahisa, Akiyama, Chie, Yasuhara, Rika, Mishima, Kenji, Maruyama, Toshifumi, Kohda, Chikara, Tanaka, Kazuo, Potempa, Jan, Yasuda, Hisataka, Baba, Kazuyoshi, Kamijo, Ryutaro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140917/
https://ncbi.nlm.nih.gov/pubmed/24755218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520510
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares