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Lysine-specific gingipain promotes lipopolysaccharide- and active vitamin D(3)-induced osteoclast differentiation by degrading osteoprotegerin
Porphyromonas gingivalis is one of the major pathogens of periodontitis, a condition characterized by excessive alveolar bone resorption by osteoclasts. The bacterium produces cysteine proteases called gingipains, which are classified according to their cleavage-site specificity into lysine-specific...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4188552/ https://ncbi.nlm.nih.gov/pubmed/19102726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081469 |
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