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Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells

Mesenchymal stem cells (MSCs) are promising source of cell‐based regenerative therapy. In consideration of the risk of allosensitization, autologous MSC‐based therapy is preferred over allogenic transplantation in patients with chronic kidney disease (CKD). However, it remains uncertain whether adeq...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Kim, Hyoungnae, Yu, Mi Ra, Lee, Haekyung, Kwon, Soon Hyo, Jeon, Jin Seok, Han, Dong Cheol, Noh, Hyunjin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884040/
https://ncbi.nlm.nih.gov/pubmed/33524231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13317
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