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Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells

Mesenchymal stem cells (MSCs) are promising source of cell‐based regenerative therapy. In consideration of the risk of allosensitization, autologous MSC‐based therapy is preferred over allogenic transplantation in patients with chronic kidney disease (CKD). However, it remains uncertain whether adeq...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Kim, Hyoungnae, Yu, Mi Ra, Lee, Haekyung, Kwon, Soon Hyo, Jeon, Jin Seok, Han, Dong Cheol, Noh, Hyunjin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884040/
https://ncbi.nlm.nih.gov/pubmed/33524231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13317
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