Sirt1–hypoxia‐inducible factor‐1α interaction is a key mediator of tubulointerstitial damage in the aged kidney

Although it is known that the expression and activity of sirtuin 1 (Sirt1) decrease in the aged kidney, the role of interaction between Sirt1 and hypoxia‐inducible factor (HIF)‐1α is largely unknown. In this study, we investigated whether HIF‐1α could be a deacetylation target of Sirt1 and the effec...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Ryu, Dong Ryeol, Yu, Mi Ra, Kong, Kyoung Hye, Kim, Hyoungnae, Kwon, Soon Hyo, Jeon, Jin Seok, Han, Dong Cheol, Noh, Hyunjin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413666/
https://ncbi.nlm.nih.gov/pubmed/30614190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12904
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