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Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells

Mesenchymal stem cells (MSCs) are promising source of cell‐based regenerative therapy. In consideration of the risk of allosensitization, autologous MSC‐based therapy is preferred over allogenic transplantation in patients with chronic kidney disease (CKD). However, it remains uncertain whether adeq...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Kim, Hyoungnae, Yu, Mi Ra, Lee, Haekyung, Kwon, Soon Hyo, Jeon, Jin Seok, Han, Dong Cheol, Noh, Hyunjin
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884040/
https://ncbi.nlm.nih.gov/pubmed/33524231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13317
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