Imaging renal mitochondrial dysfunction in chronic kidney disease: a repurposed role for [99mTc]Tc-MIBI SPECT/CT

Abstract Background [99mTc]Tc-MIBI is a conventional myocardial perfusion radiotracer, and is predominantly taken up by mitochondria in a manner dependent on mitochondrial membrane potential. This study aimed to repurpose [99mTc]Tc-MIBI for functional renal imaging to evaluate mitochondrial dysfunct...

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Prif Awduron:	Soo Bin Park, Chae Hong Lim, So-Young Jin, Yon Hee Kim, Haekyung Lee, Hyoungnae Kim, Hyunjin Noh, Jin Seok Jeon, Soon Hyo Kwon
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	SpringerOpen 2025-09-01
Cyfres:	EJNMMI Research
Pynciau:	SPECT/CT Chronic kidney disease [99mTc]Tc-MIBI MIBI Mitochondrial dysfunction
Mynediad Ar-lein:	https://doi.org/10.1186/s13550-025-01306-7
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