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Best practices for the visualization, mapping, and manipulation of R‐loops

R‐loops represent an abundant class of large non‐B DNA structures in genomes. Even though they form transiently and at modest frequencies, interfering with R‐loop formation or dissolution has significant impacts on genome stability. Addressing the mechanism(s) of R‐loop‐mediated genome destabilizati...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Chédin, Frédéric, Hartono, Stella R, Sanz, Lionel A, Vanoosthuyse, Vincent
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883053/
https://ncbi.nlm.nih.gov/pubmed/33411340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106394
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