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Best practices for the visualization, mapping, and manipulation of R‐loops

R‐loops represent an abundant class of large non‐B DNA structures in genomes. Even though they form transiently and at modest frequencies, interfering with R‐loop formation or dissolution has significant impacts on genome stability. Addressing the mechanism(s) of R‐loop‐mediated genome destabilizati...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Chédin, Frédéric, Hartono, Stella R, Sanz, Lionel A, Vanoosthuyse, Vincent
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883053/
https://ncbi.nlm.nih.gov/pubmed/33411340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106394
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