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Ultra-deep Coverage Single-molecule R-loop Footprinting Reveals Principles of R-loop Formation
R-loops are a prevalent class of non-B DNA structures that have been associated with both positive and negative cellular outcomes. DNA:RNA immunoprecipitation (DRIP) approaches based on the anti-DNA:RNA hybrid S9.6 antibody revealed that R-loops form dynamically over conserved genic hotspots. We hav...
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| Veröffentlicht in: | J Mol Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7669280/ https://ncbi.nlm.nih.gov/pubmed/32105733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.02.014 |
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