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Characterization of R-Loop Structures Using Single-Molecule R-Loop Footprinting and Sequencing
R-loops are three-stranded structures that form during transcription when the nascent RNA hybridizes with the template DNA resulting in a DNA:RNA hybrid and a looped-out single-stranded DNA (ssDNA) strand. These structures are important for normal cellular processes and aberrant R-loop formation has...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7669279/ https://ncbi.nlm.nih.gov/pubmed/32681515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0680-3_15 |
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